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This FOXO4-p53 interaction occurs within nuclear PML (promyelocytic leukemia) bodies and is critical for maintaining the viability of senescent cells without it, p53 is free to translocate to mitochondria and trigger intrinsic apoptosis

I'm curious what the sort of research and preparation is for an episode of the show

This reaction takes place in the mitochondrial matrix and is catalyzed by carnitine acyltransferase 2 (also called carnitine palmitoyltransferase 2, CPT2), which is located on the inner face of the inner mitochondrial membrane

Sources US Food and Drug Administration